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GOURI Collagen Filler

Item no.: 145033 EAN: 8800077300001
0

For visibly firmer, natural-looking skin

€83.99 net
Your PLUS customer savings €4.20 net
Packaging unit: 1 ml
In stock

Guaranteed usable: 06.08.2027

What Makes GOURI So Unique

Unlike conventional hyaluronic acid fillers that add volume, GOURI relies on a biostimulatory effect. The fully soluble active ingredient Polycaprolactone (PCL) activates fibroblasts, stimulates natural collagen synthesis, and thereby strengthens the dermal matrix in a long-lasting way. 

Thanks to its unique mechanism of action, GOURI combines two effects: 

  • Direct biostimulation – activation of collagen production for improved firmness and elasticity.
  • Long-term effect – gradual breakdown of PCL ensures continuous skin tightening over many months. 
The result is a visibly improved skin structure with natural resilience – without artificial volume enhancement or alteration of facial features.

Next-Generation Injectable Skin Booster

GOURI is the world’s first injectable collagen filler based on fully soluble polycaprolactone (PCL). It stimulates the body’s natural collagen production evenly across the face – without creating artificial volume. The result: visibly improved skin elasticity, smoothness, and firmness for several months.

Innovative Polycaprolactone (PCL) Technology

The unique, evenly soluble PCL structure in GOURI enables sustained stimulation of fibroblasts, promoting natural collagen regeneration. Unlike traditional fillers, GOURI acts biostimulatively, improving skin quality over the long term rather than simply filling wrinkles.

 

Key Features

  • Promotes the production of Type I collagen
  • Enhances skin firmness and elasticity
  • Even effect without lump formation
  • Non-volumizing filler – for natural results

Targeted Application for Visibly Smoother Skin

Standardised Injection Points for Consistent Results
GOURI is applied following a precise, standardised pattern at ten injection points across the face. These points are selected to ensure the polycaprolactone (PCL) distributes evenly within the dermis and subcutis, stimulating the body’s own collagen production throughout all facial areas – resulting in a harmonious, natural outcome. The even stimulation process enhances overall skin structure without creating unnatural volume. Often, a single treatment is sufficient to achieve visible improvements in firmness and elasticity.
Targeted Injection - Effective Distribution of Active Ingredients
The GOURI injection is administered intradermally or subcutaneously in the marked zones of the midface. The active ingredient distributes homogeneously through the tissue, stimulating fibroblasts to produce new type I collagen. This even distribution is crucial for the natural skin-tightening effect, which develops over several weeks. As PCL fully biodegrades, no foreign volume remains – the skin appears visibly fresher and denser without looking “filled.”
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Application Guidelines for Optimal Results

  • Injection plane: Dermis – subcutaneous layer
  • Needle size: 25 G, 50 mm
  • Aspiration test: Perform before injection to minimise bruising
  • Anesthesia: Local anaesthetic can be used at the physician’s discretion
  • Premixing: 1 cc of GOURI can be mixed with 0.2–0.3 cc lidocaine + epinephrine
  • Number of sessions: 1 treatment recommended; optional 1–2 follow-up sessions after 4–6 weeks
  • Combination treatments: Can be safely combined with EBD procedures (EBD first, then GOURI)
  • Interval to other treatments: Wait at least 2 weeks after GOURI before performing EBD
  • Precautions: Do not use within 4 weeks before/after COVID vaccination, acute infection, or flu-like symptoms

Technical Details

  • Premium collagen stimulator to boost the body’s own collagen synthesis
  • Supports the natural regeneration of collagen production
  • Promotes visible revitalization and smoothing of the skin
  • Provides immediate wrinkle-filling effect
  • Slows the natural ageing process of the skin
  • First injectable liquid polycaprolactone (PCL) without microparticles
  • Innovative collagen-activated polymer technology – soluble, biodegradable, and actively effective
  • Even distribution under the skin – no lumps or irregularities
  • Full-face treatment with only two injection points per half-face
  • Long-lasting cosmetic effect compared with hyaluronic acid (up to 1 year)
  • Natural degradation initiated by hydrolysis
  • Good tolerability and easy application – gentle massage suffices
  • Clinically tested: Successful completion of Phase 1 and Phase 2 studies (over 200 participants)
  • Easy storage at room temperature (5–25 °C), shelf life 24 months from production
  • ISO 13485 certified and CE-marked
  • For hygiene reasons, non-returnable
  • Manufacturer: Dexlevo Inc.
  • Contents: 1 syringe with 1 ml
Visible reduction in wrinkle depth within just a few weeks
Improved firmness and elasticity
Visible improvement in skin firmness and evenness
Naturally smooth, balanced complexion without added volume

Key Facts About GOURI

How should the GOURI filler be injected?
For first-time treatments, it is recommended to administer the GOURI filler over three sessions (1 ml per session) spaced four weeks apart. Subsequent treatments can be scheduled every 3–6 months to maintain sustained collagen stimulation.

When are the first results visible?
Depending on the patient, initial results can be seen immediately after injection, as GOURI provides an immediate smoothing effect and subtle volume enhancement. Neocollagenesis typically begins within 1–2 weeks, at which point the first long-lasting results become noticeable.

How long does the GOURI filler last?
The duration can vary between patients. Polycaprolactone (PCL) is a highly effective material that is generally absorbed by the body within 6–12 months.

Can GOURI be used with other anti-aging treatments?
GOURI is compatible with other treatments such as Botox, PRP, or hyaluronic acid fillers. It is recommended to maintain a one-month interval between different treatments.

Are there any known side effects?
As with any injectable treatment, temporary redness, swelling, or lumps may appear at the injection site, typically resolving within 1–3 days. Patients may experience a brief burning sensation during the injection, which subsides immediately afterwards. Avoid blood-thinning medications for seven days prior to treatment to reduce, but not entirely eliminate, the risk of minor bruising.

What factors can affect the effectiveness of GOURI?
Similar to hyaluronic acid fillers, certain factors may reduce the longevity of GOURI’s effects:

  • Avoid massaging or manipulating the treated area.
  • Limit prolonged sun exposure and always use sunscreen.
  • Avoid high temperatures such as saunas or steam baths where possible.
  • Do not use skincare products containing AHA, BHA, retinol, or vitamin C on the treated area.
Have any questions about GOURI Collagen Filler?
Contact our medical device product specialists for fast, expert support.
Sam Selzner Sam Selzner
Sascha Christens Sascha Christens
Yixin Chen Yixin Chen
+44 (0)20 3769 2102
Product Information

The GOURI collagen filler from Dexlevo Inc. is the first fully soluble polycaprolactone (PCL) filler designed for biostimulative skin rejuvenation. Unlike traditional hyaluronic acid fillers, GOURI does not add artificial volume. Instead, it activates the body's natural collagen production, improving skin quality from within.

Thanks to the gradual breakdown of PCL, GOURI provides long-lasting results, delivering natural tightening and a smoother, more even skin texture. The product is suitable for treating the entire facial area and can also be used in combination with energy- or laser-based treatments.

Areas of application: Face, neck, décolleté
Content: 1 ml per ampoule
Duration of effect: Approximately 12 months

Product Identification
  • Manufacturer: DexLevo
  • Manufacturer article number: 2940
  • Item no.: 145033
  • EAN: 8800077300001
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GOURI Collagen Filler
€83.99 net
Your PLUS customer savings €4.20 net